• 1. Mouri A, Noda Y, Niwa M, Matsumoto Y, Mamiya T, Nitta A, Yamada K, Furukawa S, Iwamura T, Nabeshima T. The involvement of brain-derived neurotrophic factor in 3,4-methylenedioxymethamphetamine -induced place preference and behavioral sensitization.Behav Brain Res. 329:157-165 (2017)
  • 2. Kunisawa K, Kido K, Nakashima N, Matsukura T, Nabeshima T, Hiramatsu M. Betaine attenuates memory impairment after water-immersion restraint stress and is regulated by the GABAergic neuronal system in the hippocampus. Eur J Pharmacol. 796:122-130(2017)
  • 3. Dang DK, Shin EJ, Mai AT, Jang CG, Nah SY, Jeong JH, Ledent C, Yamamoto T, Nabeshima T, Onaivi ES, Kim HC. Genetic or pharmacological depletion of cannabinoid CB1 receptor protects against dopaminergic neurotoxicity induced by methamphetamine in mice. Free Radic Biol Med.108:204-224 (2017)
  • 4. Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K. Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice. Immunol Lett. 181:94-100 (2017)
  • 5. Li ZY, Chung YH, Shin EJ, Dang DK, Jeong JH, Ko SK, Nah SY, Baik TG, Jhoo JH, Ong WY, Nabeshima T, Kim HC. YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by β-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2. J Neuroinflammation. 14:94 (2017)
  • 6. Kubo H, Hoshi M, Matsumoto T, Irie M, Oura S, Tsutsumi H, Hata Y, Yamamoto Y, Saito K. Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice. Lipids Health Dis. 16:106 (2017)
  • 7. Tran TV, Shin EJ, Jeong JH, Lee JW, Lee Y, Jang CG, Nah SY, Lei XG, Toriumi K,Yamada K, Nabeshima T, Kim HC. Protective potential of the glutathione peroxidase-1 gene in abnormal behaviors induced by phencyclidine in mice. Mol Neurobiol. (In press)
  • 8. Tran TV, Shin EJ, Nguyen LTT, Lee Y, Kim DJ, Jeong JH, Jang CG, Nah SY, Toriumi K, Nabeshima T, Yamada K, Kim HC. Protein kinase C δ gene depletion protects against methamphetamine-induced impairments in recognition memory and ERK1/2 signaling via upregulation of glutathione peroxidase-1 gene.Mol Neurobiol. (In press)
  • 9. Dang DK, Shin EJ, Tran HQ, Kim DJ, Jeong JH, Jang CG, Nah SY, Sato H, Nabeshima T, Yoneda Y, Kim HC. The role of system Xc- in methamphetamine-induced dopaminergic neurotoxicity in mice. Neurochem Int. 108:254-265 (2017)
  • 10. Alkam T, Mamiya T, Kimura N, Yoshida A, Kihara D, Tsunoda Y, Aoyama Y, Hiramatsu M, Kim HC, Nabeshima T. Prenatal nicotine exposure decreases the release of dopamine in the medial frontal cortex and induces atomoxetine-responsive neurobehavioral deficits in mice. Psychopharmacology (Berl). 234:1853-1869 (2017)
  • 11. Matsumoto Y, Niwa M, Mouri A, Noda Y, Fukushima T, Ozaki N, Nabeshima T. Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice. Psychopharmacology (Berl).(In press)
  • 12. Tashiro T, Murakami Y, Mouri A, Imamura Y, Nabeshima T, Yamamoto Y, Saito K. Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions.Behav Brain Res. 317:279-285 (2016)
  • 13. Fujigaki H, Yamamoto Y, Saito K. L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences. Neuropharmacol. 112:264-274 (2017)
  • 14. Ohta Y, Kubo H, Yashiro K, Ohashi K, Tsuzuki Y, Wada N, Yamamoto Y, Saito K. Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues.       J Physiol Sci. 67:361-372 (2017)
  • 15. Kimura A, Takemura M, Saito K, Yoshikura N, Hayashi Y, Inuzuka T. Association between naturally occurring anti-amyloid β autoantibodies and medial temporal lobe atrophy in Alzheimer’s disease. J Neurol Neurosurg Psychiatry. 88:126-31 (2017)
  • 16. Shibata Y, Hara T, Matsumoto T, Nakamura N, Nakamura H, Ninomiya S, Kitagawa J, Goto N, Nannya Y, Ito H, Kito Y, Miyazaki T, Takeuchi T, Saito K, Seishima M, Takami T, Moriwaki H, Shimizu M, Tsurumi H. Serum concentrations of l-kynurenine predict clinical outcomes of patients with peripheral T-cell lymphoma, not otherwise specified. Hematol Oncol. (In press)
  • 17. Tran TV, Shin EJ, Ko SK, Nam Y, Chung YH, Jeong JH, Jang CG, Nah SY, Yamada K, Nabeshima T, Byun JK, Kim HC. Mountain-cultivated ginseng attenuates phencyclidine-induced abnormal behaviors in mice by positive modulation of glutathione in the prefrontal cortex of mice. J Med Food.19:961-969 (2016)
  • 18. Dang DK, Shin EJ, Nam Y, Ryoo S, Jeong JH, Jang CG, Nabeshima T, Hong JS, Kim HC. Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK. J Neuroinflammation. 13:12. (2016)
  • 19. Tran HQ, Chung YH, Shin EJ, Kim WK, Lee JC, Jeong JH, Wie MB, Jang CG, Yamada K, Nabeshima T, Kim HC. High-dose dextromethorphan produces myelinoid bodies in the hippocampus of rats. J Pharmacol Sci.132:166-170 (2016)
  • 20. Shimizu C, Oki Y, Mitani Y, Tsuchiya Y, Nabeshima T. Moderate-dose Regular lifelong alcohol intake changes the intestinal flora, protects against aging, and keeps spatial memory in the senescence-accelerated mouse prone 8 (SAMP8) model. J Pharm Pharm Sci. 19:430-447 (2016)
  • 21. Mabuchi R, Hara T, Matsumoto T, Shibata Y, Nakamura N, Nakamura H, Kitagawa J, Kanemura N, Goto N, Shimizu M, Ito H, Yamamoto Y, Saito K, Moriwaki H, Tsurumi H. High serum concentration of L-kynurenine predicts unfavorable outcomes in patients with acute myeloid leukemia. Leuk Lymphoma. 57:92-98 (2016)
  • 22. Hara T, Matsumoto T, Shibata Y, Nakamura N, Nakamura H, Ninomiya S, Kitagawa J, Nannya Y, Shimizu M, Ito H, Saito K, Tsurumi H. Prognostic value of the combination of serum l-kynurenine level and indoleamine 2,3-dioxygenase mRNA expression in acute myeloid leukemia. Leuk Lymphoma.57:2208-2211(2016)
  • 23. Tanaka H, Yamamoto Y, Kashihara H, Yamazaki Y, Tani K, Fujiyoshi Y, Mineta K, Takeuchi K, Tamura A, Tsukita S. Claudin-21 has a paracellular channel role at tight junctions. Mol Cell Biol.36(6):954-64(2016)
  • 24. Tran TN, Mai HN, Shin EJ, Nam Y, Nguyen BT, Lee YJ, Jeong JH, Tran HP, Cho EH,Nah SY, Lei XG, Nabeshima T, Kim NH, Kim HC. Repeated exposure to far infrared ray attenuates acute restraint stress in mice via inhibition of JAK2/STAT3 signaling pathway by induction of glutathione peroxidase-1. Neurochem Int. 94:9-22 (2016)
  • 25. Shin EJ, Dang DK, Tran HQ, Nam Y, Jeong JH, Lee YH, Park KT, Lee YS, Jang CG, Hong JS, Nabeshima T, Kim HC. PKCγ knockout mice are protected from para- methoxymethamphetamine – induced mitochondrial stress and associated neurotoxicity in the striatum of mice. Neurochem Int.100:146-158 (2016)
  • 26. Aoyama Y, Toriumi K, Mouri A, Hattori T, Ueda E, Shimato A, Sakakibara N, Soh Y, Mamiya T, Nagai T, Kim HC, Hiramatsu M, Nabeshima T, Yamada K. Prenatal nicotine exposure impairs the proliferation of neuronal progenitors, leading to fewer glutamatergic neurons in the medial prefrontal cortex. Neuropsychopharmacology.41:578-589 (2016)
  • 27. Mouri A, Ikeda M, Koseki T, Iwata N, Nabeshima T. The ubiquitination of serotonin transporter in lymphoblasts derived from fluvoxamine-resistant depression patients. Neurosci Lett.617:22-26 (2016)
  • 28. Shibata Y, Hara T, Nagano J, Nakamura N, Ohno T, Ninomiya S, Ito H, Tanaka T, Saito K, Seishima M, Shimizu M, Moriwaki H, Tsurumi H. The role of indoleamine 2,3-dioxygenase in diethylnitrosamine-induced liver carcinogenesis. PloS One.11:e0146279 (2016)
  • 29. Uno K, Kikuchi Y, Iwata M, Uehara T, Matsuoka T, Sumiyoshi T, Okamoto Y, Jinno H, Takada T, Furukawa-Hibi Y, Nabeshima T, Miyamoto Y, Nitta A. Decreased DNA methylation in the Shati/Nat8l promoter in both patients with schizophrenia and a methamphetamine-induced murine model of schizophrenia-like phenotype.PLoS One. 11:e0157959 (2016)
  • 30. Ogiso H, Ito H, Ando T, Arioka Y, Kanbe A, Ando K, Ishikawa T, Saito K, Hara A, Moriwaki H, Shimizu M, Seishima M. The deficiency of indoleamine 2,3-dioxygenase aggravates the CCl4-induced liver fibrosis in mice. PloS One 11:e0162183 (2016)
  • 31. Toriumi K, Oki M, Muto E, Tanaka J, Mouri A, Mamiya T, Kim HC, Nabeshima T. Prenatal phencyclidine treatment induces behavioral deficits through impairment of GABAergic interneurons in the prefrontal cortex.Psychopharmacology (Berl). 233:2373-2381 (2016)
  • 32. Murakami Y, Ishibashi T, Tomita E, Imamura Y, Tashiro T, Watcharanurak K, Nishikawa M, Takahashi Y, Takakura Y, Mitani S, Fujigaki H, Ohta Y, Kubo H, Mamiya T, Nabeshima T, Kim HC, Yamamoto Y, Saito K. Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1.Sci Rep. 6:29920 (2016)
  • 33. Goto A, Mouri A, Nagai T, Yoshimi A, Ukigai M, Tsubai T, Hida H, Ozaki N, Noda Y. Involvement of the histamine H4 receptor in clozapine-induced hematopoietic toxicity: Vulnerability under granulocytic differentiation of HL-60 cells. Toxicol Appl Pharmacol. 306:8-16 (2016)


  • 1. Shin EJ, Dang DK, Tran TV, Tran HQ, Jeong JH, Nah SY, Jang CG, Yamada K, Nabeshima T, Kim HC. Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors. Arch Pharm Res.40:403-428 (2017)
  • 2. Shin EJ, Tran HQ, Nguyen PT, Jeong JH, Nah SY, Jang CG, Nabeshima T, Kim HC. Role of Mitochondria in Methamphetamine-Induced Dopaminergic Neurotoxicity: Involvement in Oxidative Stress, Neuroinflammation, and Pro-apoptosis-A .Neurochem Res. (In press)
  • 3. 長谷川章、三宅裕理子、吉見 陽、肥田裕丈、毛利彰宏、山田清文、尾崎紀夫、鍋島俊隆、野田幸裕. JSNP Excellent presentation award for CINP2016: A strategy for traeating in deficits of social behaviors induced by exposure to social defeat stress as jeveniles. 日本神経精神薬理学雑誌37:93-94(2017)
  • 4. 齋藤 邦明. 脳神経疾患における治療標的としてのトリプトファン-キヌレニン代謝酵素. 日本神経精神薬理学雑誌37:103-107 (2017)
  • 5. 毛利 彰宏,近藤 麻生,木村 真理,横山 美里,柳本 佳南,椿井 朋,後藤 綾,肥田 裕丈,德倉 達也,木村 宏之,吉見 陽,尾崎 紀夫,鍋島 俊隆,野田 幸裕. セロトニントランスポーターのユビキチン化を指標とした口腔灼熱症候群に認められる抑うつ状態のバイオマーカー探索. 名城大学総合研究所紀要.21:221-224 (2016)
  • 6. 野田 幸裕,肥田 裕丈,毛利 彰宏,長谷川 章,成宮 周,古屋敷 智之,尾崎 紀夫, 鍋島 俊隆. 周産期における免疫応答異常による精神機能への影響 : Prostaglandin E₂ (PGE₂)-EP1受容体シグナル伝達系の関与. 名城大学総合研究所紀要. 21:93-96 (2016)
  • 7. 荒木 理沙(名古屋大学医学部附属病院薬剤部)執筆、鍋島俊隆 監修 タグリッソⓇ錠 –抗悪性腫瘍剤- やくほう紙(スズケングループ発行)第73号2016年9月発行
  • 8. 杉本 智哉(名古屋大学医学部附属病院薬剤部)執筆、鍋島俊隆 監修 フィコンパⓇ錠 –新規抗てんかん剤-やくほう紙(スズケングループ発行)第72号2016年8月発行
  • 9. 廣瀬 聖美(名古屋大学医学部附属病院薬剤部)執筆、鍋島俊隆 監修 レパーサⓇ錠2皮下注- 高コレステロール血症治療薬- やくほう紙(スズケングループ発行)第71号2016年6月発行


  • 1. 吉尾 隆、鍋島 俊隆、ほか 編集 『visual core pharma 薬物治療学(第6版)』、南山堂、東京、2017年3月14日
  • 2. 鍋島 俊隆 ほか、編集 『New薬理学(改訂第7版)』、南山堂、東京、2017年3月23日



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